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GM mais põhjustab rottidel maksa- ja neeruprobleeme



Märts 2007


Archives of Environmental Contamination and Technology on avaldatud uurimus, mille väitel ilmnesid geenmuundatud maisiga MON863 90 päeva jooksul söödetud rottide maksas ja neerudes mürgituse tunnused.

MON863 on geenmuundatud maisitüvi, mis on resistentne maisi juureussidele ning on EL-s heaks kiidetud kasutamiseks loomasöödana alates 2005. a. ning inimtoiduna alates 2006. a. jaanuarist.

Vt. ajakirja Archives of Environmental Contamination and Technology artiklit siin:

 90 days rats_stat.


"New analysis of a rat feeding study with a genetically modified maize reveals signs of
hepatorenal toxicity"
Authors: G.-E. Seralini, D. Cellier, J. Spiroux de Vendomois


Health risk assessment of genetically modified organisms
(GMOs) cultivated for food or feed is under debate throughout the world,
and very little data have been published on mid- or long-term
toxicological studies with mammals. One of these studies performed under
the responsibility of Monsanto Company with a transgenic corn MON863 has
been subjected to questions from regulatory reviewers in Europe, where
it was finally approved in 2005. This necessitated a new assessment of
kidney pathological findings, and the results remained controversial. An
Appeal Court action in Germany (Münster) allowed public access in June
2005 to all the crude data from this 90-day rat-feeding study. We
independently re-analyzed these data. Appropriate statistics were added,
such as a multivariate analysis of the growth curves, and for
biochemical parameters comparisons between GMO-treated rats and the
controls fed with an equivalent normal diet, and separately with six
reference diets with different compositions. We observed that after the
consumption of MON863, rats showed slight but dose-related significant
variations in growth for both sexes, resulting in 3.3% decrease in
weight for males and 3.7% increase for females. Chemistry measurements
reveal signs of hepatorenal toxicity, marked also by differential
sensitivities in males and females. Triglycerides increased by 24-40% in
females (either at week 14, dose 11% or at week 5, dose 33%,
respectively); urine phosphorus and sodium excretions diminished in
males by 31-35% (week 14, dose 33%) for the most important results
significantly linked to the treatment in comparison to seven diets
tested. Longer experiments are essential in order to indicate the real
nature and extent of the possible pathology; with the present data it
cannot be concluded that GM corn MON863 is a safe product.

Gilles-Eric Seralini
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